Endocrine Abstracts

Background: Maternal hyperthyroidism (MH) during late pregnancy is associated with adverse neonatal outcomes but the effects of MH in early gestation when managed in a specialised joint obstetric endocrine clinic setting is unclear. Objectives: To evaluate the obstetric and neonatal outcomes of maternal hyperthyroidism presenting during early gestation. Methods: Endocrine and obstetric record of 40 pregnancies with active hyperthyroidism managed in the antenatal endocrine clin...

Objective: Propylthioracil (PTU) when given long term has recently been implicated in the development of antineutrophil cytoplasmic antibody (ANCA) related systemic vasculitis. We describe a case of ANCA positive athropathy induced by long term PTU therapy. Methods: Assessment was based on patient's symptoms, signs, serum markers and treatment outcome as revealed by case notes and patient review. A Medline search for PTU related vasculitis was also performed. Results: A 27-yea...

Mediastinal location of a functional parathyroid adenoma is a rare but a well recognised entity and Tc-99M sestamibi scan is an established imaging technique for the succesful localization of such tissues with a sensitivity and specificity of more than 90%. Here we report an unusual case of primary hyperparathyroidism presenting with a 3-cm mediastinal mass with no evidence of abnormal uptake of the isotope and subsequent resolution of the mass on further imaging.<p class...